config/livewire.php file and change this:
'middleware_group' => ['web'],
'middleware_group' => [ 'web', 'universal', InitializeTenancyByDomain::class, // or whatever tenancy middleware you use ],
Now you can use Livewire both in the central app and the tenant app.
Also make sure to enable universal routes.
And if you're using file uploads, read the Real-time facades page of the documentation. Livewire uses real-time facades in the uploading logic.